Advances of mesenchymal stem cells transplantation for treating intervertebral disc degeneration

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007 May;21(5):502-6
Authors: Liang T, Liu H

OBJECTIVE: To introduce the research of mesenchymal stem cells(MSCs) transplantation for treating intervertebral disc degeneration.

METHODS: The recent original articles about the MSCs transplantation for treating intervertebral disc degeneration were extensively reviewed.

RESULTS: Transplanted MSCs in intervertebral disc can express chrondcyte-like phenotype in certain conditions, increase matrix synthesis and release intervertebral disc degeneration.

CONCLUSION: MSCs transplantation for treating intervertebral disc degeneration may be a future approach.

PMID: 17578291 [PubMed – indexed for MEDLINE]