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Disk Disease Library

Adipose-Derived Stem Cells and Their Place in Regenerative Medicine

By | Adipose (fat) Tissue, Auto-Immune Diseases, Auto-Immune Diseases Library, Auto-Immune Hepatitis Library, Blog, Diabetes Library, Disk Disease Library, Elbow and Hand Surgery Library, Featured, General Orthopedics Library, Knee Pain, Knee Surgery Library, Multiple Sclerosis Library, News and Events, Orthopedics, Orthopedics Library, Rheumatoid Arthritis Library, Stem Cell Research Studies, Uncategorized | No Comments

Although there was a time when the mention of “stem cells” brought to mind procedures and practices involving neonatal cell extraction and painful bone marrow surgeries, regenerative medicine researchers have provided a strong case for adult stem cells in the treatment of disease.  In fact, for use in the majority…

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Stromal Stem Cells, Platelet Rich Plasma, and the Treatment of Osteoarthritis

By | Blog, Currently Studying, Disk Disease Library, Featured, General Orthopedics Library, Hip Surgery Library, Knee Pain, Knee Surgery Library, News and Events, Orthopedics, Orthopedics Library, Rheumatoid Arthritis Library, Shoulder Surgery Library, Stem Cell Research Studies | No Comments

Stromal Vascular Fraction (SVF), a suspension consisting of a wide variety of beneficial stem cell types, which can be easily obtained from a patient’s own adipose tissue.  Utilizing a simple and minimally-invasive outpatient procedure, a small amount of a patient’s unused fat tissue is removed and transformed into a ready…

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Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration.

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Biomaterials. 2003 Sep;24(20):3531-41 Authors: Sakai D, Mochida J, Yamamoto Y, Nomura T, Okuma M, Nishimura K, Nakai T, Ando K, Hotta T Intervertebral disc degeneration is considered to be one of the major causes of low back pain. Despite this irreversible phenomenon, attempts to decelerate disc degeneration using various techniques…

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Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells.

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Gene Ther. 2004 Jan;11(1):34-41 Authors: Ito H, Goater JJ, Tiyapatanaputi P, Rubery PT, O’Keefe RJ, Schwarz EM Deficiencies in skeletal tissue repair and regeneration lead to conditions like osteoarthritis, osteoporosis and degenerative disc disease. While no cure for these conditions is available, the use of human bone marrow derived-mesenchymal stem…

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Bone mesenchymal stem cells transplanted into rabbit intervertebral discs can increase proteoglycans.

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Clin Orthop Relat Res. 2005 Jan;(430):219-26 Authors: Zhang YG, Guo X, Xu P, Kang LL, Li J We sought to determine whether transplanted allogeneic bone mesenchymal stem cells can survive and increase the amount of proteoglycans in intervertebral discs. We used the rabbit intervertebral disc as a model, creating three…

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New strategies for disc repair: novel preclinical trials.

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J Orthop Sci. 2005;10(1):112-8 Authors: Mochida J Degeneration of lumbar intervertebral discs is a major cause of low back complaints, an irreversible occurrence with no currently available treatment. Furthermore, various surgical procedures can accelerate disc degeneration. On the other hand, recent experimental studies on disc cells have demonstrated an important…

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