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General Orthopedics Library

Stromal Stem Cells, Platelet Rich Plasma, and the Treatment of Osteoarthritis

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Stromal Vascular Fraction (SVF), a suspension consisting of a wide variety of beneficial stem cell types, which can be easily obtained from a patient’s own adipose tissue.  Utilizing a simple and minimally-invasive outpatient procedure, a small amount of a patient’s unused fat tissue is removed and transformed into a ready…

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Fat-Derived Stem Cells bring Regeneration to Degenerative Joint Disease Sufferers

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Degenerative Joint Disease Commonly called “degenerative joint disease,” (DJD), osteoarthrosis or osteoarthritis (OA) is the commonest form of arthritis. It is ubiquitous and causes the afflicted joints to deteriorate or “degenerate” progressively, losing articular cartilage, eroding into bone, often accompanied by ligament laxity. The disease affects approximately 27 million Americans…

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Orthopedics: bone substitutes and beyond.

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Orthopedics. 2010 Sep 7; 33(9) : 661. doi: 10.3928/01477447-20100722-31. Allograft alternatives: bone substitutes and beyond. Goodman SB. Abstract Excessive wear debris, deep infection, periprosthetic fracture, and other causes can lead to bone loss associated with total joint replacements. When performing revisions, surgeons are often preoccupied by the failed implant and…

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Cartilage regeneration by bone marrow cells-seeded scaffolds.

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Cartilage regeneration by bone marrow cells-seeded scaffolds. Wegener B, Schrimpf FM, Bergschmidt P, Pietschmann MF, Utzschneider S, Milz S, Jansson V, Müller PE. Abstract Different approaches exist for the treatment of small articular cartilage defects. Several studies show comparable results for autologous chondrocyte implantation (ACI) and microfracture. Unfortunately, the fibrocartilage…

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Cartilage regeneration in osteoarthritis.

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Expert Opin Biol Ther. 2009 Nov; 9(11) : 1399-405. Stem cell therapy for cartilage regeneration in osteoarthritis. Koelling S, Miosge N. Georg August University, Tissue Regeneration Work Group, Department of Prosthodontics, Abteilung Prothetik im Zentrum ZMK, Robert-Koch-Str. 40, Goettingen, D- 37075, Germany. Abstract Enhancing the regeneration potential of hyaline cartilage…

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