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General Orthopedics Library

Orthopedics: bone substitutes and beyond.

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Orthopedics. 2010 Sep 7; 33(9) : 661. doi: 10.3928/01477447-20100722-31. Allograft alternatives: bone substitutes and beyond. Goodman SB. Abstract Excessive wear debris, deep infection, periprosthetic fracture, and other causes can lead to bone loss associated with total joint replacements. When performing revisions, surgeons are often preoccupied by the failed implant and…

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Cartilage regeneration by bone marrow cells-seeded scaffolds.

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Cartilage regeneration by bone marrow cells-seeded scaffolds. Wegener B, Schrimpf FM, Bergschmidt P, Pietschmann MF, Utzschneider S, Milz S, Jansson V, Müller PE. Abstract Different approaches exist for the treatment of small articular cartilage defects. Several studies show comparable results for autologous chondrocyte implantation (ACI) and microfracture. Unfortunately, the fibrocartilage…

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Cartilage regeneration in osteoarthritis.

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Expert Opin Biol Ther. 2009 Nov; 9(11) : 1399-405. Stem cell therapy for cartilage regeneration in osteoarthritis. Koelling S, Miosge N. Georg August University, Tissue Regeneration Work Group, Department of Prosthodontics, Abteilung Prothetik im Zentrum ZMK, Robert-Koch-Str. 40, Goettingen, D- 37075, Germany. Abstract Enhancing the regeneration potential of hyaline cartilage…

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Enhancing chondrogenesis from adipose tissue.

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Tissue Eng Part A. 2009 Jul; 15(7) : 1543-51. Combination of transforming growth factor-beta2 and bone morphogenetic protein 7 enhances chondrogenesis from adipose tissue-derived mesenchymal stem cells. Kim HJ, Im GI Abstract In this study, the authors examined combinations of growth factors that induce effective chondrogenesis from adipose tissue-derived mesenchymal…

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