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Multiple Sclerosis Library

Fat-Derived Stem Cells bring Regeneration to Degenerative Joint Disease Sufferers

By | General Orthopedics Library, Knee Surgery Library, Multiple Sclerosis Library, News and Events, Rheumatoid Arthritis Library, Stem Cell Research Studies, Uncategorized | No Comments

Degenerative Joint Disease Commonly called “degenerative joint disease,” (DJD), osteoarthrosis or osteoarthritis (OA) is the commonest form of arthritis. It is ubiquitous and causes the afflicted joints to deteriorate or “degenerate” progressively, losing articular cartilage, eroding into bone, often accompanied by ligament laxity. The disease affects approximately 27 million Americans…

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Stem Cell Transplantation May Halt Disease Progression of Multiple Sclerosis

By | Multiple Sclerosis Library, Stem Cell Research Studies | No Comments

What is Multiple Sclerosis? Multiple Sclerosis (MS) is caused by the immune system malfunctioning and attacking the insulating myelin sheaths, surrounding the nerve fibers in the spinal cord and the brain by mistake. It causes problems with speech, vision, balance and movement. Over the years, the disease can turn into…

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Mechanisms of oxidative damage in multiple sclerosis and a cell therapy approach to treatment.

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Autoimmune Dis. 2010 Dec 15;2011:164608. Mechanisms of oxidative damage in multiple sclerosis and a cell therapy approach to treatment. Witherick J, Wilkins A, Scolding N, Kemp K. Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Bristol BS16 1LE, UK. Abstract Although…

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Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?

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Curr Opin Immunol. 2010 Dec;22(6):768-74. Epub 2010 Nov 17. Why should mesenchymal stem cells (MSCs) cure autoimmune diseases? Uccelli A, Prockop DJ. Department of Neurosciences Ophthalmology and Genetics, University of Genoa, Italy. auccelli@neurologia.unige.it Abstract The adult stem/progenitor cells from bone marrow and other tissues referred to as mesenchymal stem cells…

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Inflammatory cytokine induced regulation of superoxide dismutase 3 expression by human mesenchymal stem cells.

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Stem Cell Rev. 2010 Dec; 6(4) : 548-59 Inflammatory cytokine induced regulation of superoxide dismutase 3 expression by human mesenchymal stem cells. Kemp K, Gray E, Mallam E, Scolding N, Wilkins A Abstract Increasing evidence suggests that bone marrow derived-mesenchymal stem cells (MSCs) have neuroprotective properties and a major mechanism…

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A consensus statement addressing mesenchymal stem cell transplantation for multiple sclerosis: it’s time!

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2010 Dec;6(4):500-6. A consensus statement addressing mesenchymal stem cell transplantation for multiple sclerosis: it’s time! Siatskas C, Payne NL, Short MA, Bernard CC. Monash immunology and stem cell laboratories, Monash University, Clayton, Victoria, 3800, Australia. christopher.siatskas@monash.edu Abstract Multiple sclerosis is a neurodegenerative disease of the central nervous system that is…

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Stem cells as therapeutics for neurodegenerative disorders?

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Stem cells as therapeutics for neurodegenerative disorders? Mattson MP. Laboratory of Neurosciences, National Institute on Aging GRC 4F01, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA. mattsonm@grc.nia.nih.gov Abstract Aging is associated with a progressive increase in the risk of several prominent neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease,…

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Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population.

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Ann Hematol. 2010 Sep 25; Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population. Xu J, Ji BX, Su L, Dong HQ, Sun WL, Wan SG, Liu YO, Zhang P, Liu CY Abstract To evaluate clinical…

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