Category

Rheumatoid Arthritis Library

Stromal Vascular Fraction Therapy: A Multi-Discipline Approach

By | Adipose (fat) Tissue, Auto-Immune Diseases, Blog, Featured, News and Events, Orthopedics, Osteoarthritis, Platelet Rich Plasma, Rheumatoid Arthritis Library, Stem Cell Research Studies, Stromal Vascular Fraction | No Comments

In our recent series of blogs and articles, we have highlighted specific diseases and conditions that were effectively managed using Stromal Vascular Fraction (SVF) or its derivative component adipose-derived stem cells.  For more information on how these multipotent regenerative agents of change impact the health outcomes of patients with osteoarthritis,…

Read More

Take a Knee: Osteoarthritis and Platelet-Rich-Plasma

By | Auto-Immune Diseases, Blog, Osteoarthritis, Platelet Rich Plasma, Rheumatoid Arthritis Library | No Comments

Sufferers of Osteoarthritis Osteoarthritis is a degenerative connective tissue disease, and as the most common form of arthritis affects millions of people worldwide.  This debilitating condition occurs as the cartilage that protects the ends of bones at the joint wears down, eventually resulting in painful bone on bone contact friction. …

Read More

Adipose-Derived Stem Cells and Their Place in Regenerative Medicine

By | Adipose (fat) Tissue, Auto-Immune Diseases, Auto-Immune Diseases Library, Auto-Immune Hepatitis Library, Blog, Diabetes Library, Disk Disease Library, Elbow and Hand Surgery Library, Featured, General Orthopedics Library, Knee Pain, Knee Surgery Library, Multiple Sclerosis Library, News and Events, Orthopedics, Orthopedics Library, Rheumatoid Arthritis Library, Stem Cell Research Studies, Uncategorized | No Comments

Although there was a time when the mention of “stem cells” brought to mind procedures and practices involving neonatal cell extraction and painful bone marrow surgeries, regenerative medicine researchers have provided a strong case for adult stem cells in the treatment of disease.  In fact, for use in the majority…

Read More

Stromal Stem Cells, Platelet Rich Plasma, and the Treatment of Osteoarthritis

By | Blog, Currently Studying, Disk Disease Library, Featured, General Orthopedics Library, Hip Surgery Library, Knee Pain, Knee Surgery Library, News and Events, Orthopedics, Orthopedics Library, Rheumatoid Arthritis Library, Shoulder Surgery Library, Stem Cell Research Studies | No Comments

Stromal Vascular Fraction (SVF), a suspension consisting of a wide variety of beneficial stem cell types, which can be easily obtained from a patient’s own adipose tissue.  Utilizing a simple and minimally-invasive outpatient procedure, a small amount of a patient’s unused fat tissue is removed and transformed into a ready…

Read More

Fat-Derived Stem Cells bring Regeneration to Degenerative Joint Disease Sufferers

By | General Orthopedics Library, Knee Surgery Library, Multiple Sclerosis Library, News and Events, Rheumatoid Arthritis Library, Stem Cell Research Studies, Uncategorized | No Comments

Degenerative Joint Disease Commonly called “degenerative joint disease,” (DJD), osteoarthrosis or osteoarthritis (OA) is the commonest form of arthritis. It is ubiquitous and causes the afflicted joints to deteriorate or “degenerate” progressively, losing articular cartilage, eroding into bone, often accompanied by ligament laxity. The disease affects approximately 27 million Americans…

Read More

Stem Cells in Orthopedic Research

By | Knee Surgery Library, Rheumatoid Arthritis Library, Stem Cell Research Studies, Uncategorized | No Comments

For many of the millions of arthritis sufferers, stem cell research seems like an exciting prospect in a dystopian healthcare system advocating debilitating surgeries and progressively higher doses of steroids.  Luckily, stem cell therapy is becoming an increasingly popular alternative treatment for a variety of conditions, including degenerative joint disease…

Read More

Regulation of TNFalpha and IL1beta in rheumatoid arthritis synovial fibroblasts by leukotriene B4.

By | Rheumatoid Arthritis Library | No Comments

Rheumatol Int. 2010 Jul;30(9):1183-9 Authors: Xu S, Lu H, Lin J, Chen Z, Jiang D Arachidonic acid metabolites, such as leukotriene B4 (LTB4), are known to play an important role in pathogenesis of rheumatoid arthritis (RA). Apart from leukocytes, RA synovial fibroblasts (RASF) produce a broad array of inflammatory mediators…

Read More

Monoclonal antibodies: new therapeutic agents for autoimmune hemolytic anemia?

By | Rheumatoid Arthritis Library | No Comments

Endocr Metab Immune Disord Drug Targets. 2008 Mar;8(1):62-8 Authors: D’Arena G, Taylor RP, Cascavilla N, Lindorfer MA Conventional treatment of autoimmune hemolytic anemia (AIHA) comprises corticosteroids and splenectomy and/or other immunosuppressive drugs for refractory/relapsed patients. Monoclonal antibodies (MoAbs) rituximab and alemtuzumab have gained widespread acceptance in the management of B-cell…

Read More

Bmx regulates LPS-induced IL-6 and VEGF production via mRNA stability in rheumatoid synovial fibroblasts.

By | Rheumatoid Arthritis Library | No Comments

Biochem Biophys Res Commun. 2008 Jun 13;370(4):599-602 Authors: Palmer CD, Mutch BE, Page TH, Horwood NJ, Foxwell BM Discordant cytokine production is characteristic of chronic inflammatory conditions like rheumatoid arthritis (RA), and anti-cytokine therapeutics are becoming routinely used to treat RA in the clinic. Fibroblasts from rheumatoid synovium have been…

Read More