In our recent series of blogs and articles, we have highlighted specific diseases and conditions that were effectively managed using Stromal Vascular Fraction (SVF) or its derivative component adipose-derived stem cells. For more information on how these multipotent regenerative agents of change impact the health outcomes of patients with osteoarthritis,…
Sufferers of Osteoarthritis Osteoarthritis is a degenerative connective tissue disease, and as the most common form of arthritis affects millions of people worldwide. This debilitating condition occurs as the cartilage that protects the ends of bones at the joint wears down, eventually resulting in painful bone on bone contact friction. …
Although there was a time when the mention of “stem cells” brought to mind procedures and practices involving neonatal cell extraction and painful bone marrow surgeries, regenerative medicine researchers have provided a strong case for adult stem cells in the treatment of disease. In fact, for use in the majority…
Stromal Vascular Fraction (SVF), a suspension consisting of a wide variety of beneficial stem cell types, which can be easily obtained from a patient’s own adipose tissue. Utilizing a simple and minimally-invasive outpatient procedure, a small amount of a patient’s unused fat tissue is removed and transformed into a ready…
Degenerative Joint Disease Commonly called “degenerative joint disease,” (DJD), osteoarthrosis or osteoarthritis (OA) is the commonest form of arthritis. It is ubiquitous and causes the afflicted joints to deteriorate or “degenerate” progressively, losing articular cartilage, eroding into bone, often accompanied by ligament laxity. The disease affects approximately 27 million Americans…
For many of the millions of arthritis sufferers, stem cell research seems like an exciting prospect in a dystopian healthcare system advocating debilitating surgeries and progressively higher doses of steroids. Luckily, stem cell therapy is becoming an increasingly popular alternative treatment for a variety of conditions, including degenerative joint disease…
Rheumatol Int. 2010 Jul;30(9):1183-9 Authors: Xu S, Lu H, Lin J, Chen Z, Jiang D Arachidonic acid metabolites, such as leukotriene B4 (LTB4), are known to play an important role in pathogenesis of rheumatoid arthritis (RA). Apart from leukocytes, RA synovial fibroblasts (RASF) produce a broad array of inflammatory mediators…
Endocr Metab Immune Disord Drug Targets. 2008 Mar;8(1):62-8 Authors: D’Arena G, Taylor RP, Cascavilla N, Lindorfer MA Conventional treatment of autoimmune hemolytic anemia (AIHA) comprises corticosteroids and splenectomy and/or other immunosuppressive drugs for refractory/relapsed patients. Monoclonal antibodies (MoAbs) rituximab and alemtuzumab have gained widespread acceptance in the management of B-cell…
Biochem Biophys Res Commun. 2008 Jun 13;370(4):599-602 Authors: Palmer CD, Mutch BE, Page TH, Horwood NJ, Foxwell BM Discordant cytokine production is characteristic of chronic inflammatory conditions like rheumatoid arthritis (RA), and anti-cytokine therapeutics are becoming routinely used to treat RA in the clinic. Fibroblasts from rheumatoid synovium have been…
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