Stem cell therapy for erectile dysfunction

Zhonghua Nan Ke Xue. 2009 Oct; 15(10) : 937-40
Progress in researches on stem cell therapy for erectile dysfunction.

Jiang YB, Gou X

Abstract
Erectile dysfunction (ED) commonly results from endothelial dysfunction and erectile nerve damage. Recent researches have focused on the preclinical studies of stem cell-based therapies targeted at repairing penile endothelium and protecting erectile nerves. Early studies showed that stem cell- or gene-modified stem cell-based therapies may have enduring efficacy and eventually lead to a cure for ED. Such stem cells as embryonic, mesenchymal, muscle-derived and adipose-derived ones and endothelial progenitor cells all have differentiation potentials and obvious advantages in protecting and repairing both nervi erigentes and corpus cavernosum vascular endothelial cells. Stem cellbased therapies promise to be an effective approach to human erectile dysfunction.

PMID: 20112746 [PubMed – indexed for MEDLINE]