The adipose-derived stem cell: looking back and looking ahead.

 MolBiol Cell. 2010 Jun;21(11):1783-7. Epub 2010 Apr 7.

The adipose-derived stem cell: looking back and looking ahead.

Zuk PA.

Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. pzuk@mednet.ucla.edu

Abstract

In 2002, researchers at UCLA published a manuscript in Molecular Biology of the Cell describing a novel adult stem cell population isolated from adipose tissue-the adipose-derived stem cell (ASC). Since that time, the ASC has gone on to be one of the most popular adult stem cell populations currently being used in the stem cell field. With multilineage mesodermal potential and possible ectodermal and endodermal potentials also, the ASC could conceivably be an alternate to pluripotent ES cells in both the lab and in the clinic. In this retrospective article, a historical perspective on the ASC is given together with exciting new applications for the stem cell being considered today.

PMID: 20375149 [PubMed – indexed for MEDLINE]