ALS, also known as Lou Gehrig’s disease, is a debilitating neurologic disease that results from the destruction of upper and lower motor neurons in the brain and spinal cord. Amyotrophic Lateral Sclerosis is associated with rapidly progressive weakness, muscle wasting, spasticity, and difficulty breathing, swallowing and speaking. There is no known cause for amyotrophic lateral sclerosis and genetics are implicated in only 5% of cases. There is no known cure for the physical defects associated with ALS. Many investigators are looking at using the regenerative properties of cell therapy to mitigate the impact of ALS on the nervous system.
A robust fundraising campaign called the “Ice Bucket Challenge” raised over 100 million dollars for the ALS Association, and the majority of the proceeds went directly toward research into finding a cure. According to the ALS Association, “Stem cells have emerged as a major tool for research into the causes of ALS.” Research with embryonic stem cells has been limited because of the ethical concerns with taking stem cells from human embryos. The ALS Association is currently funding research into the potential of induced pluripotent stem cells (iPS cells). Unlike embryonic stem cells, iPS cells can be collected from an adult patient’s skin. The iPS cells are then cultured in a dish with certain combinations of cytokines and growth factors to become motor neurons. Clinical trials are still in their early stages, and it’s unclear whether the new motor neurons would have any resistance to progressive motor neuron death caused by amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis – Gulf Coast Stem Cell & Regenerative Medicine Center
Being an affiliate member of the Cell Surgical Network(CSN,) Gulf Coast Stem Cell & Regenerative Medicine Center(GCSC&RMC) uses specific SVF protocols that attempt to utilize the immuno-regulatory, regenerative, and anti-inflammatory properties of SVF (rich in mesenchymal stem cells and growth factors). Special measures are taken to optimize transport of the SVF across the blood-brain barrier to improve central nervous system uptake. This is all done as an outpatient at the time of SVF harvesting and procurement. The entire cellular surgical procedure takes approximately three hours.
We at GCSC&RMC care about our patients and understand their difficulties. We take pride in the time we spend caring for them and deploying, what we believe, is the best protocol to help them achieve their goals.
By filling out the Contact From herewith, we would have the opportunity of addressing any questions and concerns about our methodology and protocols for ALS.