Treatment protocols at Gulf Coast Stem Cell & Regenerative Medicine Center rely upon the conveniently accessible deposits of stem cells found among fat cells in adipose tissue. The adipose tissue is extracted in a simple outpatient procedure, effectively a short round of mini-liposuction, which is much less disruptive and painful than the process of harvesting bone marrow cells. After the adipose tissue is extracted, it is carefully separated into its different components. The fatty portion is separated from the liquid portion, which is the stromal vascular fraction (SVF), and contains many different kinds of cells and active molecules, like growth factors and cytokines. A few of these elements are discussed below.
Mesenchymal Stem Cells (MSCs): these are multipotent cells that derive from the middle layer of the embryo—the mesoderm—that consists of a loose mass of unspecialized cells, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop. They have the potential to differentiate and become a variety of different kinds of cells, depending on where they are and what is required of them. MSCs are found in every tissue of the body, but different tissues have different concentrations. Adipose tissue appears to have the highest concentration of stem cells in the body; which is understandable when one considers that fat is an excellent storage tissue for food energy, and stem cells provide an endless and ready supply of multipotent cells that can become fat cells for rapid storage.
Growth factors and cytokines: these are the main messengers used by the body, which can affect inflammation, immunity, and various other functions, including cell growth and regeneration and repair of tissue.
There are over 300 different kinds of molecules and a myriad of different types of cells in SVF, so the exact components and proportions of SVF may vary among people and from site to site in the same person. Generally, however, it is widely accepted that most elements of the SVF play a role in the regeneration of surrounding or even distant tissues. With the treatment protocols at Gulf Coast Stem Cell & Regenerative Medicine Center, we transfer this concentration of regenerative cells and messenger elements to another part of the patient’s body where healing and regeneration is desirable. The efficacy of stem cell therapy in individual patients is still the focus of ongoing intense research to identify the potential beneficiaries of SVF treatments and why certain individuals benefit more than others. Meanwhile, our stem cell therapy protocols are based on the principle of bioavailability, which is more easily understood in wound infections. A few hundred bacteria settling in an open wound from dust may not cause wound infection, but a few million implanted during a bite would. The precipitous increased in bacterial numbers favors infection. Likewise, when a higher concentration of regenerative cells and healing molecules is made available at a site of damage or injury, the increased biological availability of these elements favors regeneration and repair. So the bodily systems that have been damaged by disease or trauma can then be given the opportunity to make use of the regenerative cells and beneficial healing substances present in SVF. Furthermore, stem cells have an inbuilt homing characteristic that attracts them to sites of inflammation, damage, and degeneration.
To learn more about our treatment protocols with stem cells and SVF, contact us for a consultation.
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